Dr Damian Muñoz

Dr Damian Muñoz
Curso mínima invasiva south beach

miércoles, 13 de noviembre de 2013

The association of lumbar intervertebral disc degeneration on magnetic resonance imaging with body mass index in overweight and obese adults: A population-based study




Se ha comprobado, aunque pueda parecer obvio, que son más frecuentes las degeneraciones discales de la columna lumbar en las personas obesas y con sobrepeso.

Arthritis Rheum, 05/2012,

 “The association of lumbar intervertebral disc degeneration on magnetic resonance imaging with body mass index in overweight and obese adults: A population-based study”.


Estudio transversal de 2.599 voluntarios chinos de ambos sexos con edad media de 42 años, mediante resonancia magnética de la columna lumbar para comprobar la presencia, el alcance y la gravedad de la degeneración discal con relación a su índice de masa corporal (kg/m2). La degeneración del disco se observó en el 72,7% sujetos. Las personas con sobrepeso y obesidad presentaron degeneración discal de forma significativamente mayor que el resto. También fue significativamente mayor el número de niveles degenerados, la severidad global de la degeneración del disco, y la etapa final la degeneración del disco con estrechamiento del espacio discal.

 2012 May;64(5):1488-96. doi: 10.1002/art.33462.

The association of lumbar intervertebral disc degeneration on magnetic resonance imaging with body mass index in overweight and obese adults: a population-based study.

Source

University of Hong Kong, Pokfulam, Hong Kong, China. dsamartzis@msn.com

Abstract

OBJECTIVE:

To investigate the association of being overweight or obese with the presence, extent, and severity of lumbar disc degeneration on magnetic resonance imaging (MRI) in adults.

METHODS:

A population-based cross-sectional study of 2,599 southern Chinese volunteers was conducted. Subjects underwent radiographic and clinical assessment, and weight and height were measured. Sagittal T2-weighted MRIs of the lumbar spine were obtained. The presence, extent, and severity of disc degeneration and additional radiographic and clinical parameters were assessed. Asian-modified body mass index (BMI) (kg/m(2) ) categories were used. Odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated.

RESULTS:

The study included 1,040 men and 1,559 women (mean age 41.9 years). Disc degeneration was noted in 1,890 subjects (72.7%). BMI was significantly higher in subjects with disc degeneration (mean 23.3 kg/m(2) ) than in subjects without degeneration (mean 21.7 kg/m(2) ) (P < 0.001). A significant increase in the number of degenerated levels (P < 0.001), global severity of disc degeneration (P < 0.001), and end-stage disc degeneration with disc space narrowing (P < 0.001) was noted with elevated BMI, in particular in overweight and obese subjects. In the adjusted multivariate logistic regression model, there was a positive linear trend (r(2) = 0.99) between BMI and the overall presence of disc degeneration in overweight (OR 1.30 [95% CI 1.03-1.62]) and obese (OR 1.79 [95% CI 1.17-2.74]) subjects. End-stage disc degeneration with disc space narrowing was significantly more pronounced in obese subjects (adjusted OR 1.72 [95% CI 1.23-2.41] [reference normal weight]).

CONCLUSION:

Our findings, in one of the largest studies to systematically assess lumbar disc degeneration on MRI, indicated a significant association between the presence, extent, and global severity of disc degeneration with weight in overweight and obese adults.
Copyright © 2012 by the American College of Rheumatology.
PMID:
 
22287295
 
[PubMed - indexed for MEDLINE] 
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